Shanghai Chest Hospital上海交通大学医学院附属胸科医院
Zhou Zhen
Medical Oncology

Zhou Zhen

周箴

Chief Physician

Shanghai Chest Hospital上海交通大学医学院附属胸科医院· Shanghai

Areas of Expertise

Non-small cell lung cancer (NSCLC)Advanced lung cancerLung cancer with homologous recombination deficiency (HRD)HER2-mutant NSCLCFGFR-altered NSCLCLung nodule evaluation and managementClinical trial participation for advanced and refractory lung cancer

Professional Biography

Dr. Zhou Zhen is Chief Physician in Thoracic Oncology at Shanghai Chest Hospital, Shanghai. Clinical expertise includes Non-small cell lung cancer (NSCLC) — EGFR-mutant, HER2-mutant, and FGFR-altered subtypes, Advanced lung cancer — immunotherapy, targeted therapy, and combination regimens, Lung cancer with homologous recombination deficiency (HRD) — predictive biomarker-guided therapy, HER2-mutant NSCLC — pyrotinib-based regimens. Co-first/co-corresponding author on study demonstrating that homologous recombination deficiency (HRD) predicts therapeutic outcomes of immunotherapy-based combinations in advanced lung cancer — published in Journal of Hematology & Oncology 2022 (PMID 35585646); establishing a novel predictive biomarker framework for lung cancer immunotherapy patient selection. Clinical Fellowship, Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, University of Texas — advanced training in lung cancer systemic therapy at the world's highest-volume lung cancer center. Active site investigator in multiple Phase II/III lung cancer trials at a center ranked among China's top thoracic hospitals.

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